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As Ryoka Systems Inc.
1987 - Entered the scientific and technical computing field
1997 - Signed distributor agreement with Chemical Computing Group (CCG)
1998 - Signed distributor agreements with SCM and Gaussian Inc.
1999 - Signed distributor agreement with SciCo (now Materials Design)
2001 - Signed distributor agreements with COSMOlogic (now part of Dassault Systèmes BIOVIA) and AEON Technology
2002 - Signed distributor agreement with ChemInnovation Began sales of CCG products to Southeast Asian countries
2005 - Signed distributor agreements with Daylight Chemical Information Systems and Partek (now part of Illumina)
2006 - Signed distributor agreement with Scienomics
2007 - Signed distributor agreement with BioSolveIT
2015 - Signed distributor agreement with Collaborative Drug Discovery
2016 - Signed distributor agreement with Scilligence
As MOLSIS Inc.
2016 - MOLSIS Inc. established
2017 - Acquired the software business operations of the Scientific and Technical Systems Division from Ryoka Systems Inc.
Signed distributor agreements with Chemotargets and MN-AM
2018 - Relocated head office to Hatchobori, Chuo-ku, Tokyo
2023 - Signed distributor agreement with MedBioinformatics Solutions
2025 - Signed distributor agreement with Hanson Wade
